AGER Rabbit Polyclonal Antibody (CAB1395)
- SKU:
- CAB1395
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | AGER Rabbit Polyclonal Antibody |
SKU: | CAB1395 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-330 of human AGER (NP_001127.1). |
Sequence: | IGEP LVLK CKGA PKKP PQRL EWKL NTGR TEAW KVLS PQGG GPWD SVAR VLPN GSLF LPAV GIQD EGIF RCQA MNRN GKET KSNY RVRV YQIP GKPE IVDS ASEL TAGV PNKV GTCV SEGS YPAG TLSW HLDG KPLV PNEK GVSV KEQT RRHP ETGL FTLQ SELM VTPA RGGD PRPT FSCS FSPG LPRH RALR TAPI QPRV WEPV PLEE VQLV VEPE GGAV APGG TVTL TCEV PAQP SPQI HWMK DGVP LPLP PSPV LILP EIGP QDQG TYSC VATH SSHG PQES RAVS ISII EPGE EGPT A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RAGE; sRAGE; SCARJ1; AGER |
Positive Sample: | A-549,NCI-H460,Mouse small intestine,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).
Purification Method: | Affinity purification |
Gene ID: | 177 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |