AGER Rabbit Polyclonal Antibody (CAB13264)
- SKU:
- CAB13264
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | AGER Rabbit Polyclonal Antibody |
SKU: | CAB13264 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-210 of human AGER (NP_001127.1). |
Sequence: | GAPK KPPQ RLEW KLNT GRTE AWKV LSPQ GGGP WDSV ARVL PNGS LFLP AVGI QDEG IFRC QAMN RNGK ETKS NYRV RVYQ IPGK PEIV DSAS ELTA GVPN KVGT CVSE GSYP AGTL SWHL DGKP LVPN EKGV SVKE QTRR HPET GLFT LQSE LMVT PARG GDPR PTFS CSF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:5000 - 1:10000 |
Synonyms: | RAGE; sRAGE; SCARJ1; AGER |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 43kDa |
Observed MW: | 45kDa/55kDa |
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).
Purification Method: | Affinity purification |
Gene ID: | 177 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |