The AGBL4 Polyclonal Antibody (PACO00375) is a valuable tool for researchers studying AGBL4, a protein involved in the regulation of microtubule dynamics and cell division. This antibody, generated in rabbits, exhibits high specificity and reactivity in human samples, making it suitable for a range of applications such as Western blot and immunofluorescence.AGBL4, also known as ATP/GTP binding protein-like 4, plays a crucial role in maintaining the stability of microtubules, which are essential for various cellular processes like cell division and intracellular transport.
Dysregulation of AGBL4 has been implicated in cancer development and progression, making it a potential target for cancer therapy research.By specifically detecting and binding to AGBL4 protein, this antibody allows researchers to study the expression and localization of AGBL4 in different cell types and conditions. Understanding the function of AGBL4 can provide valuable insights into its role in cancer biology and may lead to the development of novel therapeutic strategies targeting this protein.
Antibody Name:
AGBL4 Antibody
Antibody SKU:
PACO00375
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human AGBL4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
