AGBL2 Antibody (PACO36602)
- SKU:
- PACO36602
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | AGBL2 Antibody (PACO36602) |
| Antibody SKU: | PACO36602 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Cytosolic carboxypeptidase 2 protein (10-270AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: AGBL2 antibody at 8µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 105, 50, 33 kDa. Observed band size: 105 kDa. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO36602 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO36602 at dilution of 1:100. |
| Background: | Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. |
| Synonyms: | Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2), AGBL2, CCP2 |
| UniProt Protein Function: | AGBL2: Metallocarboxypeptidase that may play a role in the processing of tubulin. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.4.17.-; ProteaseChromosomal Location of Human Ortholog: 11p11.2Cellular Component: centriole; cytosolMolecular Function: zinc ion binding; metallocarboxypeptidase activityBiological Process: proteolysis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5U5Z8 |
| NCBI GenInfo Identifier: | 31657119 |
| NCBI Gene ID: | 79841 |
| NCBI Accession: | NP_079059.2 |
| UniProt Secondary Accession: | Q5U5Z8,Q53FV5, Q8IV57, Q9H5C0, A8MPX2 |
| UniProt Related Accession: | Q5U5Z8 |
| Molecular Weight: | 104,194 Da |
| NCBI Full Name: | cytosolic carboxypeptidase 2 |
| NCBI Synonym Full Names: | ATP/GTP binding protein-like 2 |
| NCBI Official Symbol: | AGBL2Â Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | cytosolic carboxypeptidase 2 |
| UniProt Protein Name: | Cytosolic carboxypeptidase 2 |
| UniProt Synonym Protein Names: | ATP/GTP-binding protein-like 2 |
| Protein Family: | Cysteine proteinase |
| UniProt Gene Name: | AGBL2Â Â |
| UniProt Entry Name: | CBPC2_HUMAN |
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