The AGBL2 Antibody (PAC015342) is a high-quality polyclonal antibody specifically designed for research involving AGBL2, a key protein involved in various cellular processes. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.AGBL2, also known as ATP/GTP-binding protein-like 2, is a protease that plays a critical role in regulating protein degradation and turnover within cells.
Its involvement in these processes makes it a valuable target for research in fields such as cell biology, cancer biology, and neurodegenerative diseases. By targeting the AGBL2 protein, researchers can gain valuable insights into the mechanisms underlying cellular function and dysfunction, providing a deeper understanding of disease pathways and potential therapeutic targets. The AGBL2 Antibody (PAC015342) is an essential tool for studying AGBL2 and its implications in various biological contexts.
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO15342(AGBL2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: 293T cell, Primary antibody: PACO15342(AGBL2 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute.
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO15342(AGBL2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Background:
AGBL2 is a 902 amino acid, cytoplasmic protein belonging to the peptidase M14 family. CCP2 is considered a metallocarboxypeptidase that may play a role in the processing of tubulin. CCP2 binds one zinc ion per subunit as a cofactor and exists as three alternatively spliced isoforms.
Synonyms:
ATP/GTP binding protein-like 2
UniProt Protein Function:
AGBL2: Metallocarboxypeptidase that may play a role in the processing of tubulin. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.4.17.-; ProteaseChromosomal Location of Human Ortholog: 11p11.2Cellular Component: centriole; cytosolMolecular Function: zinc ion binding; metallocarboxypeptidase activityBiological Process: proteolysis
