The AGBL2 Polyclonal Antibody (PACO00542) is a valuable tool for researchers studying AGBL2, a protein involved in cellular processes such as microtubule severing and cytoskeletal organization. This antibody, produced in rabbits, is highly specific to human AGBL2 and has been validated for use in Western blot applications.AGBL2, also known as ATP/ADP hydrolase, plays a crucial role in regulating microtubule dynamics, which is essential for cell division, migration, and organization. Dysregulation of AGBL2 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.
By using the AGBL2 Polyclonal Antibody, researchers can effectively detect and analyze AGBL2 expression in different cell types, allowing for a better understanding of its function in normal and disease states. This antibody is a valuable tool for studies in cell biology, cancer research, and drug development aimed at targeting AGBL2 for therapeutic purposes.
Antibody Name:
AGBL2 Antibody
Antibody SKU:
PACO00542
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the C-terminal region of human CCP2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AGBL2: Metallocarboxypeptidase that may play a role in the processing of tubulin. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.4.17.-; ProteaseChromosomal Location of Human Ortholog: 11p11.2Cellular Component: centriole; cytosolMolecular Function: zinc ion binding; metallocarboxypeptidase activityBiological Process: proteolysis
