AGAP1 Antibody (PACO18527)
- SKU:
- PACO18527
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
AGAP1 Antibody (PACO18527)
The AGAP1 Polyclonal Antibody (PACO18527) is a valuable tool for researchers studying AGAP1, a protein involved in various cellular processes such as endocytosis and vesicle trafficking. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. It specifically targets the AGAP1 protein, allowing for accurate detection and analysis in a wide range of cell types.AGAP1, also known as Arf-GAP with GTPase, plays a crucial role in regulating intracellular trafficking pathways and cell signaling events.
Its involvement in these processes makes it a promising target for research in fields such as cell biology, neurobiology, and cancer biology. By understanding the functions of AGAP1, researchers can uncover new insights into disease mechanisms and potential therapeutic targets.Overall, the AGAP1 Polyclonal Antibody is a reliable tool for investigating the functions of AGAP1 in various biological contexts, opening up new possibilities for groundbreaking research in molecular and cellular biology.
| Antibody Name: | AGAP1 Antibody (PACO18527) |
| Antibody SKU: | PACO18527 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human AGAP1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18527(AGAP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human liver cancer tissue, hela cells, mouse lung tissue, Primary antibody: PACO18527(AGAP1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18527(AGAP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. |
| Synonyms: | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
| UniProt Protein Function: | GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q9UPQ3 |
| NCBI GenInfo Identifier: | 80978930 |
| NCBI Gene ID: | 116987 |
| NCBI Accession: | NP_001032208 |
| UniProt Secondary Accession: | Q9UPQ3,Q541S5, Q6P9D7, Q9NV93, B2RTX7 |
| UniProt Related Accession: | Q9UPQ3 |
| Molecular Weight: | 94/89kd |
| NCBI Full Name: | arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform 1 |
| NCBI Synonym Full Names: | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
| NCBI Official Symbol: | AGAP1Â Â |
| NCBI Official Synonym Symbols: | GGAP1; AGAP-1; CENTG2; cnt-g2Â Â |
| NCBI Protein Information: | arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 |
| UniProt Protein Name: | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 |
| UniProt Synonym Protein Names: | Centaurin-gamma-2; Cnt-g2; GTP-binding and GTPase-activating protein 1; GGAP1 |
| Protein Family: | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein |
| UniProt Gene Name: | AGAP1Â Â |
| UniProt Entry Name: | AGAP1_HUMAN |
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