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Alpha-Fetoprotein (AFP) Rabbit Polyclonal Antibody (CAB0200)

SKU:
CAB0200
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 1 Anti-AFP Antibody CAB0200
  • Cell Biology Antibodies 1 Anti-AFP Antibody CAB0200
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Alpha-Fetoprotein (AFP) Rabbit Polyclonal Antibody
SKU:CAB0200
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 360-609 of human Alpha-Fetoprotein (Alpha-Fetoprotein (AFP)) (NP_001125.1).
Sequence:RRHP QLAV SVIL RVAK GYQE LLEK CFQT ENPL ECQD KGEE ELQK YIQE SQAL AKRS CGLF QKLG EYYL QNAF LVAY TKKA PQLT SSEL MAIT RKMA ATAA TCCQ LSED KLLA CGEG AADI IIGH LCIR HEMT PVNP GVGQ CCTS SYAN RRPC FSSL VVDE TYVP PAFS DDKF IFHK DLCQ AQGV ALQT MKQE FLIN LVKQ KPQI TEEQ LEAV IADF SGLL EKCC QGQE QEVC FAEE GQKL ISKT RAAL GV
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:AFPD; FETA; HPAFP; Alpha-Fetoprotein (AFP)
Positive Sample:HepG2,Mouse liver,Rat liver
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:69kDa
Observed MW:69kDa

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Purification Method:Affinity purification
Gene ID:174
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using Alpha-Fetoprotein (AFP) Rabbit pAb (CAB0200) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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