Alpha-Fetoprotein (AFP) Rabbit Polyclonal Antibody (CAB16750)
- SKU:
- CAB16750
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | Alpha-Fetoprotein (AFP) Rabbit Polyclonal Antibody |
SKU: | CAB16750 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 395-609 of Alpha-Fetoprotein (AFP) (NP_001125.1). |
Sequence: | DKGE EELQ KYIQ ESQA LAKR SCGL FQKL GEYY LQNA FLVA YTKK APQL TSSE LMAI TRKM AATA ATCC QLSE DKLL ACGE GAAD IIIG HLCI RHEM TPVN PGVG QCCT SSYA NRRP CFSS LVVD ETYV PPAF SDDK FIFH KDLC QAQG VALQ TMKQ EFLI NLVK QKPQ ITEE QLEA VIAD FSGL LEKC CQGQ EQEV CFAE EGQK LISK TRAA LGV |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | AFPD; FETA; HPAFP; Alpha-Fetoprotein (AFP) |
Positive Sample: | HepG2,Mouse liver,Mouse kidney,Rat plasma,Rat liver |
Cellular Localization: | Secreted. |
Calculated MW: | 69kDa |
Observed MW: | 75kDa |
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Purification Method: | Affinity purification |
Gene ID: | 174 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |