Afp Antibody (PACO24799)
- SKU:
- PACO24799
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Afp Antibody (PACO24799)
The AFP Polyclonal Antibody (PAC024799) offered by AssayGenie is a vital tool for researchers studying Alpha-fetoprotein (AFP), a key biomarker for liver cancer and other diseases. This specific antibody is produced through polyclonal antibody production and is highly reactive with human samples, making it an excellent choice for Western blot applications.AFP is a glycoprotein that is typically produced by the liver during fetal development, and elevated levels of AFP in adult blood can indicate certain types of cancer, including liver cancer. This antibody binds specifically to AFP, allowing for accurate detection and analysis in various sample types, aiding researchers in their investigations into cancer biology and diagnostics.
By using the AFP Polyclonal Antibody from AssayGenie, researchers can further their understanding of the role of AFP in cancer development and progression, potentially leading to advancements in diagnosis and treatment methods. This antibody is a valuable tool for studies focused on liver cancer, as well as other diseases where AFP levels may be a relevant biomarker.
| Antibody Name: | Afp Antibody (PACO24799) |
| Antibody SKU: | PACO24799 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Mouse, Rat, Human |
| Immunogen: | Recombinant Mouse Alpha-fetoprotein protein (18-605AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Afp antibody at 10µg/ml Lane 1: HepG2 whole cell lysate Lane 2: Rat liver tissue Lane 3: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 68 kDa Observed band size: 68 kDa . |
| Background: | Binds estrogens, fatty acid, and metals. |
| Synonyms: | Alpha-fetoprotein (Alpha-1-fetoprotein) (Alpha-fetoglobulin), Afp |
| UniProt Protein Function: | AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Cellular Component: cytoplasm; extracellular region; extracellular space Molecular Function:beta-glucuronidase activity; metal ion binding Biological Process: ovulation from ovarian follicle; progesterone metabolic process; sexual reproduction; transport |
| UniProt Code: | P02772 |
| NCBI GenInfo Identifier: | 163310738 |
| NCBI Gene ID: | 11576 |
| NCBI Accession: | NP_031449.3 |
| UniProt Secondary Accession: | P02772,Q3UJD0, |
| UniProt Related Accession: | P02772 |
| Molecular Weight: | 67.3 kDa |
| NCBI Full Name: | alpha-fetoprotein |
| NCBI Synonym Full Names: | alpha fetoprotein |
| NCBI Official Symbol: | Afp  |
| NCBI Protein Information: | alpha-fetoprotein |
| UniProt Protein Name: | Alpha-fetoprotein |
| UniProt Synonym Protein Names: | Alpha-1-fetoprotein; Alpha-fetoglobulin |
| Protein Family: | Alpha-fetoprotein |
| UniProt Gene Name: | Afp  |
| UniProt Entry Name: | FETA_MOUSE |
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