AFF4 Rabbit Polyclonal Antibody (CAB4644)
- SKU:
- CAB4644
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AFF4
- AF5Q31
- CHOPS
- MCEF
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | AFF4 Rabbit Polyclonal Antibody |
SKU: | CAB4644 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human AFF4 (NP_055238.1). |
Sequence: | MNRE DRNV LRMK ERER RNQE IQQG EDAF PPSS PLFA EPYK VTSK EDKL SSRI QSML GNYD EMKD FIGD RSIP KLVA IPKP TVPP SADE KSNP NFFE QRHG GSHQ SSKW TPVG PAPS TSQS QKRS SGLQ SGHS SQRT SAGS SSGT NSSG QRHD RESY NNSG SSSR KKGQ HGSE HSKS RSSS PGKP QAVS SLNS SHSR SHGN DHHS KEHQ RSKS PRDP DANW |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MCEF; CHOPS; AF5Q31; AFF4 |
Positive Sample: | U-87MG,HeLa,293T,LO2,MCF7,Mouse pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 127kDa |
Observed MW: | 150kDa |
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23).
Purification Method: | Affinity purification |
Gene ID: | 27125 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |