The AFAP1L2 Polyclonal Antibody (CAB15916) is a highly specific research tool designed for the study of AFAP1L2, a protein involved in cell signaling and cytoskeletal organization. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications.AFAP1L2, also known as actin filament-associated protein 1-like 2, plays a crucial role in regulating the actin cytoskeleton, which is essential for cell shape, movement, and division. Dysregulation of AFAP1L2 has been linked to various diseases, including cancer and neurological disorders.
By targeting AFAP1L2 with this antibody, researchers can investigate its function and potential as a therapeutic target in these disease contexts.Moreover, the AFAP1L2 Polyclonal Antibody offers the versatility to analyze AFAP1L2 expression in different cell types and experimental conditions, making it an invaluable tool for studies in cell biology, cancer research, and neuroscience. By understanding the role of AFAP1L2 at the molecular level, researchers can uncover new insights into disease mechanisms and develop novel treatment strategies.
Product Name:
AFAP1L2 Rabbit Polyclonal Antibody
SKU:
CAB15916
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AFAP1L2 (NP_001001936.1).
Enables SH2 domain binding activity; SH3 domain binding activity; and protein tyrosine kinase activator activity. Involved in several processes, including positive regulation of epidermal growth factor receptor signaling pathway; regulation of gene expression; and regulation of mitotic cell cycle. Located in cytosol and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
84632
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using AFAP1L2 Rabbit pAb (CAB15916) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
