The AFAP1 Polyclonal Antibody (CAB3478) is a valuable tool for researchers studying AFAP1, a protein involved in cell signaling and cytoskeletal organization. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot experiments.AFAP1, also known as actin filament-associated protein 1, plays a crucial role in cell motility and adhesion, making it a key player in processes such as cell migration and invasion.
Dysregulation of AFAP1 has been linked to cancer progression and metastasis, making it a promising target for cancer research.By using the AFAP1 Polyclonal Antibody, researchers can detect and analyze AFAP1 protein levels in a variety of cell types, providing valuable insights into its function and potential role in disease. This antibody is a valuable tool for studies in cell biology, cancer research, and other fields where AFAP1 is a key player.
Product Name:
AFAP1 Rabbit Polyclonal Antibody
SKU:
CAB3478
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 461-730 of human AFAP1 (NP_940997.1).
The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
60312
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AFAP1 antibody (CAB3478) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
