The AF-Le Purified Mouse TCR Monoclonal Antibody (H57-597) is a specialized antibody designed for research involving T Cell Receptor (TCR) proteins in mouse models. This monoclonal antibody, known as HB218, is produced through a purification process that ensures high specificity and sensitivity in detecting mouse TCR proteins.The H57-597 antibody is particularly valuable for studies focused on investigating T cell function, activation, and immune responses in mouse models. It is suitable for a variety of immunological assays, including flow cytometry, immunoprecipitation, and immunohistochemistry, allowing for precise detection and analysis of TCR expression levels and localization in different cell populations.
By targeting the TCR complex, this antibody enables researchers to explore the role of T cells in immune responses, autoimmune diseases, infectious diseases, and cancer. Its reliable performance and reproducibility make it an essential tool for advancing our understanding of T cell biology and developing therapeutic strategies that modulate T cell function in various disease contexts.Overall, the AF-Le Purified Mouse TCR Monoclonal Antibody (H57-597) represents a crucial reagent for immunology research, providing valuable insights into T cell behavior and function in mouse models, ultimately contributing to the development of novel treatments and immunotherapies.
AF/LE Purified Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
None (AF/LE)
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Gene ID:
21577
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.