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Low Endotoxin Purified Anti-Mouse Ly6G Antibody [1A8] (AGEL1370)

SKU:
AGEL1370
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€229 - €1,219
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Description

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Low Endotoxin Purified Anti-Mouse Ly6G Antibody [1A8]

The AF-Le Purified Mouse LY6G Monoclonal Antibody (1A8) (AGEL1370) is a powerful tool for research targeting LY6G, a cell surface protein widely used as a marker for polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs). This monoclonal antibody, produced in mice, demonstrates high specificity and sensitivity in various experimental applications, including flow cytometry and immunohistochemistry.LY6G, also known as Gr-1, is a critical marker for identifying and studying PMN-MDSCs, a subset of immune cells with immunosuppressive properties. These cells play a significant role in modulating immune responses in conditions such as cancer, inflammation, and infection. By targeting LY6G with this monoclonal antibody, researchers can accurately detect and quantify PMN-MDSCs in cell populations, tissues, or tumor microenvironments, advancing our understanding of immune regulation and potential therapeutic targets.

The AF-Le Purified Mouse LY6G Monoclonal Antibody (1A8) (AGEL1370) is a valuable resource for immunologists, oncologists, and researchers studying immune modulation and disease pathogenesis. Its specificity and reliability make it an essential tool for investigations aiming to unravel the complex interactions between immune cells and the tumor microenvironment, paving the way for innovative therapeutic strategies targeting PMN-MDSCs in cancer and other immune-related disorders.

Product Title:Low Endotoxin Purified Anti-Mouse Ly6G Antibody [1A8]
SKU:AGEL1370
Size:50µg, 500µg, 1mg
Clone No:1A8
Synonyms:Lymphocyte antigen 6G;Ly-6G;Ly-6G.1;Ly6g;
Host Species:Rat
Reactivity:Mouse
Application:FCM;Depletion
Isotype:Rat IgG2a, κ
Isotype Control:AF/LE Purified Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P35461
Gene ID:546644
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Lymphocyte antigen 6 complex, locus G (Ly-6G), a 21-25 kD GPI-anchored protein, is expressed on the majority of myeloid cells in bone marrow and peripheral granulocytes.

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