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Low Endotoxin Purified Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL1099)

SKU:
AGEL1099
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Applications:
FC
$227 - $1,115
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Description

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Low Endotoxin Purified Anti-Mouse/Human CD11b Antibody [M1/70]

The Mouse/Human CD11b Monoclonal Antibody (M1/70) from AssayGenie (AGEL1099) is a potent tool for researchers studying CD11b, a key integrin receptor involved in immune cell adhesion and migration. This highly purified monoclonal antibody is designed to specifically target CD11b in both mouse and human samples, providing reliable and accurate detection in a variety of experimental settings.CD11b, also known as integrin alpha M, is a critical component of the innate immune response, enabling immune cells to adhere to and migrate across endothelial cells to sites of infection or inflammation. As a marker of myeloid cell activation, CD11b is widely used in immunology and inflammation research to investigate the role of myeloid cells in various diseases and immune responses.The M1/70 monoclonal antibody is validated for use in applications such as flow cytometry, immunohistochemistry, and immunoprecipitation, offering versatility for studying CD11b expression and function in different cell types and tissues.

Its high specificity and affinity for CD11b make it an essential tool for researchers interested in characterizing myeloid cell populations, studying inflammatory processes, and exploring the role of CD11b in immune regulation.Overall, the Mouse/Human CD11b Monoclonal Antibody (M1/70) from AssayGenie provides a reliable solution for investigating the function and expression of CD11b in diverse research areas, including immunology, inflammation, and infectious diseases. With its superior performance and wide range of applications, this antibody is a valuable asset for scientists aiming to deepen their understanding of immune cell biology and related pathological conditions.

Product Title:Low Endotoxin Purified Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL1099
Size:50µg, 500µg, 1mg
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:AF/LE Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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