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Low Endotoxin Purified Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL1400)

SKU:
AGEL1400
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
$275 - $1,463
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R/B220 Monoclonal Antibody (RA3-6B2) is an essential tool for researchers studying immune cell markers and B cell populations. This highly purified antibody, produced by Assay Genie, specifically targets the CD45R/B220 antigen found on B cells, facilitating precise detection and analysis in various experimental settings.CD45R, also known as B220, is a well-established marker for B lymphocytes and plays a key role in the identification and characterization of B cell subsets. The RA3-6B2 antibody binds specifically to CD45R/B220, allowing for accurate identification and isolation of B cells in flow cytometry, immunohistochemistry, or immunofluorescence experiments.

Researchers exploring the role of B cells in immunology, autoimmunity, or infectious diseases will benefit from the high specificity and sensitivity of this monoclonal antibody. With its proven effectiveness in detecting CD45R/B220 in mouse samples, the RA3-6B2 antibody is an invaluable tool for advancing research in immunology, inflammation, and related fields.

Product Title:Low Endotoxin Purified Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL1400
Size:50µg, 500µg, 1mg
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM;Cell Sep-Neg;Depletion
Isotype:Rat IgM, κ
Isotype Control:AF/LE Purified Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Gene ID:19264,5788
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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