The LE Purified Mouse CD3 Epsilon Monoclonal Antibody (145-2C11) from AssayGenie (AGEL1314) is a high-quality research tool designed for studying CD3 Epsilon, a critical component of the T cell receptor complex. This monoclonal antibody is produced from mouse cells and is validated for various applications in immunology research, including flow cytometry and immunohistochemistry.CD3 Epsilon is essential for T cell activation and function, playing a key role in antigen recognition and signal transduction. By targeting this specific protein, researchers can investigate T cell responses in various biological contexts, ranging from infectious diseases to autoimmune conditions.
The precise binding of the 145-2C11 antibody to CD3 Epsilon allows for accurate detection and analysis in experimental settings, providing valuable insights into T cell behavior and immune system dynamics.With its specificity and reliability, the LE Purified Mouse CD3 Epsilon Monoclonal Antibody (145-2C11) is an indispensable tool for those exploring the complexities of T cell biology and the mechanisms underlying immune responses. Trust AssayGenie to deliver high-performance reagents that advance your research endeavors and deepen your understanding of immune system function.
AF/LE Purified Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
None (AF/LE)
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P22646
Gene ID:
12501
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.