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Low Endotoxin Purified Anti-Human/Mouse IL-5 Antibody [TRFK5] (AGEL2062)

SKU:
AGEL2062
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Applications:
FC
€229 - €1,219
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Description

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Low Endotoxin Purified Anti-Human/Mouse IL-5 Antibody [TRFK5]

The Purified Human/Mouse IL-5 Monoclonal Antibody (TRFK5, AGEL2062) from Assay Genie is a cutting-edge tool designed for researchers studying interleukin-5 (IL-5), a key cytokine involved in immune responses and inflammatory processes. This monoclonal antibody is meticulously purified and validated for both human and mouse samples, providing high specificity and reliability in a variety of experimental applications.IL-5 is a crucial cytokine that plays a pivotal role in promoting the growth, differentiation, and activation of eosinophils, a type of white blood cell involved in allergic reactions and defense against parasites. By targeting IL-5, researchers can gain insights into the complex mechanisms underlying allergic diseases, asthma, and other immune-related disorders.

The TRFK5 monoclonal antibody binds specifically to IL-5, allowing for precise detection and localization of this important cytokine in various biological samples.With its exceptional quality and specificity, the Purified Human/Mouse IL-5 Monoclonal Antibody (TRFK5, AGEL2062) is a valuable asset for scientists conducting research in immunology, allergy, inflammation, and related fields. By using this advanced antibody, researchers can delve deeper into the functions and regulation of IL-5, paving the way for novel therapeutic interventions and advancements in the treatment of immune-mediated conditions.

Product Title:Low Endotoxin Purified Anti-Human/Mouse IL-5 Antibody [TRFK5]
SKU:AGEL2062
Size:50µg, 500µg, 1mg
Clone No:TRFK5
Synonyms:Interleukin-5;IL-5;B-cell differentiation factor I;T-cell replacing factor;TRF;
Host Species:Rat
Reactivity:Human;Mouse
Application:ICFCM;Depletion;Neut
Isotype:Rat IgG1, κ
Isotype Control:AF/LE Purified Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P05113 P04401
Gene ID:3567,16191
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

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