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Low Endotoxin Purified Anti-Human CD4 Antibody [RPA-T4] (AGEL1385)

SKU:
AGEL1385
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$227 - $1,115
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Human CD4 Antibody [RPA-T4]

The Purified Human CD4 Monoclonal Antibody (RPA-T4) is a valuable tool for researchers studying CD4, a key cell surface marker on helper T cells that plays a vital role in immune response regulation. This monoclonal antibody, designated AGEL1385, is meticulously purified and specifically designed for use in a variety of research applications, including flow cytometry, immunohistochemistry, and functional assays.CD4 is a critical player in the adaptive immune response, facilitating communication between immune cells and coordinating the body's defense against pathogens. The RPA-T4 antibody binds specifically to CD4, allowing for precise detection and analysis of CD4-expressing cells in human samples.

Its high specificity and sensitivity make it an ideal choice for investigating immune cell populations, monitoring immune responses, and exploring the mechanisms underlying various immune-mediated diseases.Researchers in immunology, infectious diseases, and autoimmunity will find the Purified Human CD4 Monoclonal Antibody (RPA-T4) to be a valuable asset in their studies. By enabling the accurate identification and characterization of CD4-positive cells, this antibody opens up new possibilities for understanding immune system function and developing targeted therapies for immune-related disorders.

Product Title:Low Endotoxin Purified Anti-Human CD4 Antibody [RPA-T4]
SKU:AGEL1385
Size:50µg, 500µg, 1mg
Clone No:RPA-T4
Synonyms:T-cell surface glycoprotein CD4;CD4;T-cell surface antigen T4/Leu-3;CD4;
Host Species:Mouse
Reactivity:Human
Application:FCM;Block
Isotype:Mouse IgG1, κ
Isotype Control:AF/LE Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P01730
Gene ID:920
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).

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