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Low Endotoxin Purified Anti-Mouse CD86 Antibody [GL-1] (AGEL2144)

SKU:
AGEL2144
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
GL-1
Conjugation:
None (Low endotoxin)
€89 - €109

Description

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Low Endotoxin Purified Anti-Mouse CD86 Antibody [GL-1]

The AFLE-Purified Anti-Mouse CD86 Antibody (GL-1) offered by AssayGenie is a high-quality research tool designed for investigating the CD86 protein, a vital co-stimulatory molecule involved in immune cell activation. This purified monoclonal antibody, specifically tailored for recognizing mouse CD86, is ideal for a variety of immunological studies. With its high specificity and sensitivity, the GL-1 antibody is suitable for use in applications such as flow cytometry, immunohistochemistry, and functional assays.CD86, also known as B7-2, plays a crucial role in the immune response by providing the necessary co-stimulatory signals for T cell activation and proliferation.

Understanding the mechanisms behind CD86-mediated immune activation is essential for unraveling complex immune processes and developing targeted therapeutics for conditions such as autoimmune diseases, infectious diseases, and cancer.Researchers and scientists looking to explore the intricate interactions of CD86 in immune regulation can rely on the AFLE-Purified Anti-Mouse CD86 Antibody (GL-1) to provide accurate and reproducible results in their experiments. Trust AssayGenie for cutting-edge research tools that enable groundbreaking discoveries in immunology and beyond.

Product Title:Low Endotoxin Purified Anti-Mouse CD86 Antibody [GL-1]
SKU:AGEL2144
Size:50µg, 500µg, 1mg
Clone No:GL-1
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:AF/LE Purified Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P42082
Gene ID:12524
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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