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Low Endotoxin Purified Anti-Mouse CD73 Antibody [TY/23] (AGEL2176)

SKU:
AGEL2176
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
TY/23
Conjugation:
None (Low endotoxin)
€189 - €929
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse CD73 Antibody [TY/23]

The AFLE Purified Anti-Mouse CD73 Antibody (TY-23) is a high-quality research tool designed for studying CD73, a cell surface enzyme involved in immune regulation and inflammation modulation. This purified antibody, specifically targeting the mouse CD73 protein, is derived from a hybridoma culture and extensively validated for performance in various experimental techniques.CD73, also known as ecto-5'-nucleotidase, plays a crucial role in the regulation of immune responses by catalyzing the hydrolysis of extracellular adenosine monophosphate (AMP) to adenosine. This enzymatic activity has been implicated in a variety of physiological and pathological processes, including immune suppression, tumor growth, and inflammation control.

The AFLE Anti-Mouse CD73 Antibody (TY-23) enables precise detection and quantification of CD73 expression in mouse samples, making it an indispensable tool for research in immunology, oncology, and inflammatory diseases.By targeting CD73, researchers can gain valuable insights into the mechanisms underlying immune regulation and explore novel therapeutic strategies for conditions such as cancer, autoimmune disorders, and chronic inflammatory diseases. The AFLE Purified Anti-Mouse CD73 Antibody (TY-23) empowers scientists to investigate the role of CD73 in these contexts, ultimately driving advancements in our understanding of immune modulation and disease pathogenesis.

Product Title:Low Endotoxin Purified Anti-Mouse CD73 Antibody [TY/23]
SKU:AGEL2176
Size:50µg, 500µg, 1mg
Clone No:TY/23
Synonyms:5'-nucleotidase;Nt5e;5'-NT;Ecto-5'-nucleotidase;CD73;Nt5; Nte;Nt5e;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:AF/LE Purified Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q61503
Gene ID:23959
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD73 (ecto-5`-nucleotidase) is a 69 kD GPI-anchored surface protein. In mice, expression of CD73 in bone marrow is restricted to CD11b+ myeloid cells. In spleen, it is largely expressed on T cells.

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