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Low Endotoxin Purified Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL2183)

SKU:
AGEL2183
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
R17 217.1.3/TIB-219
Conjugation:
None (Low endotoxin)
$227 - $1,115
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The Mouse CD71 Purified Monoclonal Antibody (R17-217.1-3 (TIB-219)) is a versatile tool for researchers studying CD71, a transmembrane glycoprotein involved in cellular iron uptake and transport. This highly specific antibody, purified from mouse cells, is suitable for various analytical techniques such as flow cytometry, immunoprecipitation, and immunohistochemistry.CD71, also known as transferrin receptor protein 1, plays a crucial role in iron metabolism by facilitating the internalization and transport of iron-bound transferrin into cells.

Its expression levels are often indicative of cellular iron requirements and can be dysregulated in conditions like iron deficiency anemia and certain cancers. With its ability to bind specifically to CD71, this monoclonal antibody enables precise detection and visualization of the protein in various experimental settings. Researchers in the fields of cell biology, oncology, and molecular medicine can benefit from utilizing this antibody to investigate the role of CD71 in iron homeostasis, cell proliferation, and disease pathology.

Product Title:Low Endotoxin Purified Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL2183
Size:50µg, 500µg, 1mg
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:AF/LE Purified Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q62351
Gene ID:22042
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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