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Low Endotoxin Purified Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL2160)

SKU:
AGEL2160
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
FGK4.5/FGK45
Conjugation:
None (Low endotoxin)
$227 - $1,115
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Purified Anti-Mouse CD40 Antibody (FGK4.5) is a high-quality research tool offered by Assay Genie for studies involving CD40, a cell surface receptor involved in immune activation and regulation. This antibody is specifically designed for use in mouse samples and is purified to ensure maximum specificity and reproducibility in experiments. CD40 is a key player in the immune response, serving as a crucial link between innate and adaptive immunity by activating various immune cells and promoting inflammatory responses. The FGK4.5 antibody, validated for use in a range of applications such as flow cytometry and immunohistochemistry, binds specifically to the CD40 protein, enabling precise detection and analysis in different experimental setups.

With its ability to target CD40, researchers can explore various aspects of immune signaling, cell activation, and immune system modulation in the context of infectious diseases, autoimmune conditions, and cancer. The FGK4.5 antibody's high reactivity and reliability make it an indispensable tool for immunology research, offering insights into the intricate mechanisms of immune regulation and potential therapeutic targets.

Product Title:Low Endotoxin Purified Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL2160
Size:50µg, 500µg, 1mg
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:AF/LE Purified Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P27512
Gene ID:21939
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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