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Low Endotoxin Purified Anti-Mouse CD3 Antibody [17A2] (AGEL2147)

SKU:
AGEL2147
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
17A2
Conjugation:
None (Low endotoxin)
€89 - €109
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse CD3 Antibody [17A2]

The purified Anti-Mouse CD3 Antibody (17A2) from Assay Genie (AGEL2147) is a high-quality research tool designed for investigating CD3, a crucial cell surface marker involved in T cell activation and signaling. This antibody, meticulously produced for reliable performance, is derived from mouse origin and exhibits exceptional reactivity with mouse samples.With validated compatibility for various applications including flow cytometry, immunohistochemistry, and immunoprecipitation, this Anti-Mouse CD3 Antibody offers precise and specific binding to the CD3 protein. By facilitating the detection and analysis of CD3 expression in diverse cell populations, this antibody is an invaluable resource for studies in immunology, infectious diseases, and autoimmune conditions.

CD3, a component of the T cell receptor complex, plays a pivotal role in T cell activation and function, making it a central target for research aimed at understanding immune responses and developing immunotherapies. The Anti-Mouse CD3 Antibody (17A2) from Assay Genie provides researchers with a reliable tool to explore the intricate mechanisms governing T cell-mediated immunity, paving the way for advancements in immunotherapy, vaccine development, and autoimmune disease research.

Product Title:Low Endotoxin Purified Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL2147
Size:50µg, 500µg, 1mg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:AF/LE Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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