The AF-le Purified Anti-Mouse CD210 Antibody (1B1-3A) is a valuable tool for research involving the CD210 protein, a cell surface receptor known for its role in immune regulation. This antibody, derived from mouse origin, offers high specificity and sensitivity when detecting CD210 in mouse samples, and has been validated for use in various experimental applications.CD210, also known as a key regulator of immune responses, is involved in modulating inflammatory processes and immune system activity. By targeting CD210, researchers can gain insights into the mechanisms underlying immune modulation, making it a pivotal component in studies related to immunology, cancer research, and autoimmune diseases.
This purified anti-mouse CD210 antibody enables researchers to precisely detect and analyze CD210 expression in different cell types, facilitating the exploration of its function and significance in various biological contexts. With its high reactivity and specificity, this antibody is an essential tool for investigating immune regulation and the development of potential therapeutic strategies targeting CD210 in diseases such as cancer and autoimmune disorders.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
Q61727
Gene ID:
16154
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10.