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Low Endotoxin Purified Anti-Mouse CD209b Antibody [22D1] (AGEL2158)

SKU:
AGEL2158
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
22D1
Conjugation:
None (Low endotoxin)
€229 - €1,219
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse CD209b Antibody [22D1]

The AF-LE Purified Anti-Mouse CD209B Antibody (22D1) available from AssayGenie is a valuable tool for researchers studying the CD209B protein, which is also known as SIGNR3. This antibody is specifically designed for use in mouse samples and is purified for high reactivity and specificity. It is validated for various applications, including flow cytometry, immunofluorescence, and immunohistochemistry.CD209B is a cell surface molecule that plays a key role in immune response regulation and pathogen recognition. It is involved in the binding and internalization of pathogens by dendritic cells, contributing to immune defense mechanisms.

Research on CD209B is relevant to understanding host-pathogen interactions and developing strategies for combating infectious diseases.By utilizing the AF-LE Purified Anti-Mouse CD209B Antibody (22D1), researchers can accurately detect and study the CD209B protein in mouse samples, facilitating investigations into immune responses, infection mechanisms, and potential therapeutic interventions. This antibody offers high sensitivity and specificity, making it a valuable asset for studies in immunology, infectious diseases, and vaccine development.

Product Title:Low Endotoxin Purified Anti-Mouse CD209b Antibody [22D1]
SKU:AGEL2158
Size:50µg, 500µg, 1mg
Clone No:22D1
Synonyms:CD209 antigen-like protein B;Cd209b;DC-SIGN-related protein 1;DC-SIGNR1;OtB7;CD209;Cd209b;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:AF/LE Purified Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q8CJ91
Gene ID:69165
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

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