The AF-Le Purified Anti-Mouse CD1d Antibody (19G11) available at AssayGenie is a powerful tool for researchers studying immune responses in mice. This antibody specifically targets the CD1d protein, a key player in antigen presentation and immune regulation.Raised in rabbits, this purified antibody offers high reactivity and specificity for mouse CD1d, allowing for precise detection and analysis in various experimental settings. Its validation for use in techniques such as Western blotting ensures reliable results, making it a valuable asset for immunology research.CD1d is a vital component of the immune system, involved in presenting lipid antigens to specialized T cells known as iNKT cells.
This process plays a crucial role in immune surveillance and response to pathogens, making CD1d an intriguing target for investigating immune function and potential therapeutic interventions.By utilizing the AF-Le Purified Anti-Mouse CD1d Antibody (19G11), researchers can delve deeper into the intricate mechanisms of immune regulation in mouse models, paving the way for advancements in fields such as infectious diseases, autoimmune disorders, and immunotherapy development.
AF/LE Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
None (AF/LE)
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P11609
Gene ID:
12479
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD1d is a type I transmembrane protein and member of the MHC family, with a molecular weight ranging from 43-49 kD, depending on the glycosylation degree. CD1d is expressed by antigen presenting cells such as dendritic cells, monocytes, macrophages and B cells; also expressed by thymocytes and intestinal epithelial cells. CD1d present glycolipids to iNKT cells that recognize them by their Vα14i TCR.