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Low Endotoxin Purified Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL2217)

SKU:
AGEL2217
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Block
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
CXCR3-173
Conjugation:
None (Low endotoxin)
€229 - €1,219
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Anti-Mouse CD183 (CXCR3) Monoclonal Antibody (CXCR3-173) is a key tool for researchers studying immune responses in mice. This purified antibody, specifically targeting the CD183 antigen (also known as CXCR3), offers high specificity and sensitivity for detecting and analyzing CXCR3 expression in mouse samples. CXCR3 is a chemokine receptor involved in regulating immune cell migration and activation, particularly in the context of inflammation and immune responses. By targeting CXCR3, researchers can gain insights into the role of this receptor in various physiological and pathological processes, including cancer, autoimmune disorders, and infectious diseases.

The Anti-Mouse CD183 (CXCR3) Monoclonal Antibody (CXCR3-173) is generated using advanced purification techniques, ensuring high quality and reliability for experimental use. Whether conducting Western blotting, flow cytometry, or immunohistochemistry, this antibody provides a powerful tool for investigating the function and expression of CXCR3 in mouse models. Expand your research capabilities in immunology and related fields with the precise targeting of CXCR3 using this monoclonal antibody.

Product Title:Low Endotoxin Purified Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL2217
Size:50µg, 500µg, 1mg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM;Block
Isotype:Armenian Hamster IgG
Isotype Control:AF/LE Purified Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:O88410
Gene ID:12766
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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