The Purified Anti-Mouse CD18 Antibody (M18/2) offered by Assay Genie is a vital tool for researchers studying immune cell interactions and inflammatory responses in mice. This highly specific antibody is purified to ensure optimal performance and accuracy in various experimental applications.CD18 is a crucial integrin beta subunit that forms heterodimers with different alpha subunits to create various leukocyte adhesion molecules. The Anti-Mouse CD18 Antibody targets this essential protein, allowing for precise detection and characterization of CD18 expression in mouse immune cells. Its reactivity with mouse samples makes it an excellent choice for studies focusing on immune cell migration, adhesion, and immune response regulation.
By using the Anti-Mouse CD18 Antibody (M18/2), researchers can delve into the mechanisms underlying immune cell function and inflammatory processes in mouse models. This antibody is ideal for applications such as flow cytometry, immunohistochemistry, and Western blotting, providing versatile options for investigating the role of CD18 in immune system modulation and inflammatory disorders.Overall, the Purified Anti-Mouse CD18 Antibody (M18/2) from Assay Genie is a reliable and specific tool that can assist researchers in advancing their understanding of immune cell biology and inflammatory pathways in mouse models.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P11835
Gene ID:
16414
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen.