The AF-Le Purified Anti-Mouse CD132 Antibody (3E12) offered by Assay Genie is a high-quality tool designed for research involving the CD132 protein, a critical component of the immune system. This antibody, developed specifically for mouse samples, is purified for optimal performance in various applications, including immunoprecipitation and flow cytometry.CD132, also known as the common gamma chain, is a key signaling molecule involved in the function of multiple cytokine receptors, essential for immune cell development and function. The AF-Le Purified Anti-Mouse CD132 Antibody (3E12) specifically targets the CD132 protein, allowing researchers to detect and analyze its expression in different cell types with high sensitivity and specificity.
With its ability to bind to CD132, this antibody is ideal for studies in immunology, cell biology, and immune-related diseases. By enabling the precise visualization and manipulation of CD132, researchers can gain valuable insights into immune cell signaling pathways, immune responses, and potential therapeutic targets for conditions such as autoimmune diseases, immunodeficiencies, and inflammatory disorders.For reliable and reproducible results in your research, the AF-Le Purified Anti-Mouse CD132 Antibody (3E12) from Assay Genie provides a valuable tool to advance our understanding of the immune system and its role in health and disease.
AF/LE Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
None (AF/LE)
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P34902
Gene ID:
16186
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).