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Low Endotoxin Purified Anti-Mouse CD122 Antibody [5H4] (AGEL2161)

SKU:
AGEL2161
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
5H4
Conjugation:
None (Low endotoxin)
€89
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse CD122 Antibody [5H4]

The AF-le Purified Anti-Mouse CD122 Antibody (5H4) available at www.assaygenie.com is a powerful tool for researchers studying immune responses in mice. CD122, also known as the interleukin-2 receptor beta chain, is a crucial molecule involved in immune cell activation and proliferation. The 5H4 antibody is purified and specifically designed to target mouse CD122, allowing for accurate detection and analysis in various experimental settings.This high-quality antibody is raised using advanced techniques to ensure specificity and sensitivity in binding to mouse CD122. It is suitable for use in a range of applications, including flow cytometry, immunohistochemistry, and Western blotting.

By targeting CD122, researchers can gain insights into the mechanisms governing immune cell function and regulation, particularly in the context of infectious diseases, autoimmune disorders, and cancer.With its proven reliability and specificity, the AF-le Purified Anti-Mouse CD122 Antibody (5H4) is an essential tool for immunology researchers seeking to unravel the complexities of immune responses in mouse models. Unlock the potential of your research with this versatile antibody from Assay Genie.

Product Title:Low Endotoxin Purified Anti-Mouse CD122 Antibody [5H4]
SKU:AGEL2161
Size:50µg, 500µg, 1mg
Clone No:5H4
Synonyms:Interleukin-2 receptor subunit beta;Il2rb;IL-2 receptor subunit beta; IL-2R subunit beta;IL-2RB;High affinity IL-2 receptor subunit beta;p70-75;CD122;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:AF/LE Purified Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P16297
Gene ID:16185
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

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