Low Endotoxin Purified Anti-Mouse CD120b Antibody [TR75-54.7] (AGEL2165)
- SKU:
- AGEL2165
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Block
- Reactivity:
- Mouse
- Host Species:
- Armenian Hamster
- Isotype:
- Armenian Hamster IgG
- Clone:
- TR75-54.7
- Conjugation:
- None (Low endotoxin)
Frequently bought together:
Description
Product Title: | Low Endotoxin Purified Anti-Mouse CD120b Antibody [TR75-54.7] |
SKU: | AGEL2165 |
Size: | 50µg, 500µg, 1mg |
Clone No: | TR75-54.7 |
Synonyms: | Tumor necrosis factor receptor superfamily member 1B;Tnfrsf1b;Tumor necrosis factor receptor 2;TNF-R2;TNF-RII;TNFR-II;p75;p80 TNF-alpha receptor;CD120b; |
Host Species: | Armenian Hamster |
Reactivity: | Mouse |
Application: | FCM;Block |
Isotype: | Armenian Hamster IgG |
Isotype Control: | AF/LE Purified Armenian Hamster IgG Isotype Control[PIP] |
Form: | Liquid |
Conjugation: | None (AF/LE) |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Swissprot: | P25119 |
Gene ID: | 21938 |
Storage Buffer: | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state. |