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Low Endotoxin Purified Anti-Mouse CD120b Antibody [TR75-54.7] (AGEL2165)

SKU:
AGEL2165
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Block
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
TR75-54.7
Conjugation:
None (Low endotoxin)
€229 - €1,219
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse CD120b Antibody [TR75-54.7]

The AF/LE Purified Anti-Mouse CD120b Antibody (TR75-54-7) offered by Assay Genie is a cutting-edge tool for researchers studying the CD120b receptor in mice. This high-quality antibody, designed for use in various experiments, is purified and specifically tailored to detect and bind to the CD120b protein with precision.CD120b, also known as the tumor necrosis factor receptor superfamily member 1B (TNFRSF1B), plays a crucial role in mediating cellular responses to tumor necrosis factor (TNF). By targeting CD120b, researchers can gain deeper insights into the signaling pathways and biological processes impacted by TNF, shedding light on inflammation, immunity, and disease mechanisms.

The AF/LE Purified Anti-Mouse CD120b Antibody (TR75-54-7) is invaluable for immunology and cancer research, where understanding the TNF signaling cascade is paramount. By utilizing this antibody in techniques such as Western blotting or immunohistochemistry, scientists can explore the implications of CD120b activation or inhibition in various cell types and disease models.Unlock the potential of your research with the AF/LE Purified Anti-Mouse CD120b Antibody (TR75-54-7) from Assay Genie - your key to unraveling the complexities of TNF signaling and its impact on health and disease.

Product Title:Low Endotoxin Purified Anti-Mouse CD120b Antibody [TR75-54.7]
SKU:AGEL2165
Size:50µg, 500µg, 1mg
Clone No:TR75-54.7
Synonyms:Tumor necrosis factor receptor superfamily member 1B;Tnfrsf1b;Tumor necrosis factor receptor 2;TNF-R2;TNF-RII;TNFR-II;p75;p80 TNF-alpha receptor;CD120b;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM;Block
Isotype:Armenian Hamster IgG
Isotype Control:AF/LE Purified Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P25119
Gene ID:21938
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

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