The AF-LE Purified Anti-Mouse CD11a Antibody (FD441.8) is a powerful tool designed for researchers studying mouse CD11a, a cell surface molecule essential for immune cell activation and adhesion. This antibody, purified using AF-LE technology, boasts high specificity and sensitivity for mouse samples, making it a reliable choice for a range of immunological experiments.CD11a, also known as integrin alpha L, plays a key role in mediating cellular interactions involved in immune responses and inflammatory processes. By targeting CD11a, researchers can investigate its function in cell adhesion, migration, and immune cell activation pathways.
This antibody facilitates the detection and analysis of CD11a expression in various mouse cell types, providing insights into the mechanisms underlying immune response regulation.With its proven efficacy in immunology and inflammation research, the AF-LE Purified Anti-Mouse CD11a Antibody (FD441.8) is an indispensable tool for studying immune cell behavior, inflammatory diseases, and potential therapeutic targets. Harness the power of this antibody to advance your studies in immunology, inflammation, and beyond.
Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
AF/LE Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
None (AF/LE)
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P24063
Gene ID:
16408
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).