The AF Le Purified Anti-Mouse CD106 Antibody (M/K-2.7) offered by Assay Genie is a high-quality research tool designed for studying CD106, also known as VCAM-1, a cell adhesion molecule involved in immune responses and inflammation. This antibody is purified and highly specific to mouse samples, making it an excellent choice for various research applications.CD106/VCA-1 plays a crucial role in the recruitment of immune cells to sites of inflammation and is implicated in various diseases, including atherosclerosis, cancer, and inflammatory disorders. By specifically binding to CD106, the AF Le Purified Anti-Mouse CD106 Antibody (M/K-2.
7) enables precise detection and analysis of this protein in different cell types, making it invaluable for studies in immunology, vascular biology, and related fields.With its exceptional reactivity and specificity to mouse CD106, this antibody is ideal for techniques such as immunohistochemistry, flow cytometry, and immunoprecipitation, providing researchers with a reliable tool for investigating the role of CD106 in immune regulation, disease progression, and therapeutic targeting. Upgrade your research capabilities with the AF Le Purified Anti-Mouse CD106 Antibody (M/K-2.7) from Assay Genie.
Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG1, κ
Isotype Control:
AF/LE Purified Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
None (AF/LE)
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P29533
Gene ID:
22329
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).