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Low Endotoxin Purified Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL2153)

SKU:
AGEL2153
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Rat
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
MIAP410
Conjugation:
None (Low endotoxin)
€89 - €109
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The AFLE-Purified Anti-Human/Mouse/Rat CD47 Antibody (MIAP410) is a powerful tool for researchers investigating the role of CD47, a cell surface protein involved in diverse biological processes such as immune regulation, cell adhesion, and apoptosis. This highly specific antibody, purified and suitable for use in multiple species including human, mouse, and rat, is essential for studies focusing on CD47 expression and function in various experimental settings.CD47, also known as integrin-associated protein, is recognized for its roles in immune evasion, tumor progression, and signal transduction pathways.

The AFLE-Purified Anti-Human/Mouse/Rat CD47 Antibody (MIAP410) enables precise detection and analysis of CD47 protein levels, facilitating in-depth exploration of its implications in immune responses, cancer biology, and beyond. Its versatility in targeting multiple species enhances its utility in a wide array of research applications, offering valuable insights into the complex mechanisms involving CD47.

Product Title:Low Endotoxin Purified Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL2153
Size:50µg, 500µg, 1mg
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:AF/LE Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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