The AF-Le Purified Anti-Human CD3 Antibody (Ucht1) available at www.assaygenie.com is a high-quality monoclonal antibody specifically designed for research applications involving the CD3 antigen, a crucial component of the T-cell receptor complex. This antibody, purified to ensure maximum specificity and sensitivity, is raised against human samples and validated for use in a variety of immunology research techniques.The CD3 antigen, present on the surface of T lymphocytes, plays a central role in T-cell activation and signaling, making it an essential target for studies related to immune response, autoimmunity, and infectious diseases. By targeting the CD3 antigen, researchers can effectively detect and analyze T-cell populations, investigate immune cell activation, and explore the mechanisms underlying various immune-mediated conditions.
With its high reactivity and specificity for human CD3, the AF-Le Purified Anti-Human CD3 Antibody (Ucht1) is an invaluable tool for immunology research, offering reliable results and facilitating in-depth exploration of T-cell biology. Whether studying antigen recognition, T-cell differentiation, or immune system function, this antibody provides researchers with a reliable reagent to advance their understanding of T-cell biology and related immunological processes.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P07766
Gene ID:
915
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.