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Low Endotoxin Purified Anti-Human CD1a Antibody [OKT-6] (AGEL2247)

SKU:
AGEL2247
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
OKT-6
Conjugation:
None (Low endotoxin)
€229 - €1,219
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Human CD1a Antibody [OKT-6]

The Anti-Human CD1a Antibody (OKT-6) offered by AssayGenie is a purified monoclonal antibody designed for research involving CD1a, a cell surface glycoprotein expressed by cortical thymocytes, Langerhans cells, and dendritic cells. This antibody, derived from hybridoma cell culture, specifically targets the CD1a antigen in human samples and is validated for use in immunohistochemistry and flow cytometry applications.CD1a is a member of the CD1 family of transmembrane proteins involved in antigen presentation to T cells. Its expression on antigen-presenting cells plays a crucial role in immune responses and the activation of T cell receptors. By binding to CD1a, the OKT-6 Antibody enables precise detection and analysis of this protein in various cell types, thereby facilitating research in immunology, infectious diseases, and vaccine development.

The OKT-6 Antibody provides researchers with a valuable tool for investigating the role of CD1a in immune system function, autoimmune disorders, and infectious diseases. Its high specificity and reactivity make it an essential component for studies aimed at understanding antigen presentation pathways, T cell activation mechanisms, and immune responses to pathogens. Unlocking the intricacies of CD1a function is key to advancing research in immunotherapy, vaccine design, and immune-related disorders.

Product Title:Low Endotoxin Purified Anti-Human CD1a Antibody [OKT-6]
SKU:AGEL2247
Size:50µg, 500µg, 1mg
Clone No:OKT-6
Synonyms:T6; R4;CD 1a;CD1A ;T-cell surface glycoprotein CD1a;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:AF/LE Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P06126
Gene ID:909
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.

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