The AES Polyclonal Antibody (CAB7874) is a powerful tool for researchers studying AES, a transcriptional repressor involved in various cellular processes including development and differentiation. This antibody, created using rabbit immunization, shows high reactivity with both human and mouse samples, making it versatile for a wide range of research applications.Validated for use in Western blotting, this antibody binds specifically to the AES protein, facilitating accurate detection and analysis in different cell types.
Its reliability and consistency make it an excellent choice for studies in molecular biology, developmental biology, and cancer research.AES is known for its role in regulating gene expression and cell proliferation, making it a key player in various diseases including cancer and neuronal disorders. By targeting AES with this high-quality antibody, researchers can gain valuable insights into its function and potential therapeutic interventions for diseases related to AES dysregulation.
Product Name:
AES Rabbit Polyclonal Antibody
SKU:
CAB7874
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human AES (NP_945320.1).
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
166
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AES antibody (CAB7874) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
