The AER61 Monoclonal Antibody is a powerful tool for researchers studying the CD300A protein, a key regulator of immune responses. This antibody, produced through a specialized monoclonal antibody development process, offers high specificity and sensitivity for detecting and analyzing CD300A in a variety of cell types.CD300A, also known as an immune inhibitory receptor, is involved in immune regulation and plays a critical role in maintaining immune homeostasis. By inhibiting immune responses, CD300A helps to control inflammation and prevent allergic reactions. Research on CD300A is particularly important in understanding diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions, where immune dysregulation is a key factor.
The AER61 Monoclonal Antibody provides researchers with a reliable tool for investigating the function of CD300A in these disease contexts. Its high reactivity with human samples and validation for use in various applications, such as Western blotting, make it an ideal choice for studies in immunology and cancer research. By enabling the detection and analysis of CD300A protein expression, this antibody contributes to advancing our understanding of immune regulation and the development of targeted therapies for immune-related diseases.
Product Name:
AER61 Monoclonal Antibody
SKU:
CAB21166
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human AER61 (NP_775925.1).
This gene encodes an enzyme that acts in the lumen of the endoplasmic reticulum to catalyze the transfer of N-acetylglucosamine to serine or threonine residues of extracellular-targeted proteins. This enzyme modifies proteins containing eukaryotic growth factor (EGF)-like domains, including the Notch receptor, thereby regulating developmental signalling. Mutations in this gene have been observed in individuals with Adams-Oliver syndrome 4. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
285203
Clone Number:
ARC2976
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using AER61 Rabbit mAb (CAB21166) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
