ADSL Rabbit Polyclonal Antibody (CAB6278)
- SKU:
- CAB6278
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ADSL Rabbit Polyclonal Antibody |
SKU: | CAB6278 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human ADSL (NP_000017.1). |
Sequence: | MAAG GDHG SPDS YRSP LASR YASP EMCF VFSD RYKF RTWR QLWL WLAE AEQT LGLP ITDE QIQE MKSN LENI DFKM AAEE EKRL RHDV MAHV HTFG HCCP KAAG IIHL GATS CYVG DNTD LIIL RNAL DLLL PKLA RVIS RLAD FAKE RASL PTLG FTHF QPAQ LTTV GKRC CLWI QDLC MDLQ NLKR VRDD LRFR GVKG TTGT QASF LQLF EGDD HKVE QLDK MVTE KAGF KRAF IITG QTYT RKVD IEVL SVLA SLGA SVHK ICTD IRLL ANLK EMEE PFEK QQIG SSAM PYKR NPMR SERC CSLA RH |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:20 - 1:100 |
Synonyms: | ASL; AMPS; ASASE; ADSL |
Positive Sample: | Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 55kDa |
Observed MW: | 55kDa |
The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 158 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |