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ADRM1 Monoclonal Antibody [PAT34C2AT] (CPAB0552)

SKU:
CPAB0552
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT34C2AT
Applications:
ELISA
FC
€149
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Description

system_update_alt Datasheet

ADRM1 Monoclonal Antibody [PAT34C2AT] (CPAB0552)

The ADRM1 Polyclonal Antibody (CPAB0552) is a crucial tool for researchers studying ADRM1, a protein involved in the regulation of protein degradation and maintenance of cellular homeostasis. This antibody is produced in rabbits and has been extensively validated for use in Western blot applications, showing high reactivity with human samples.ADRM1, also known as the proteasome 26S subunit, is essential for the recognition and processing of ubiquitinated proteins within the cell. Dysregulation of ADRM1 function has been linked to various diseases, including cancer and neurodegenerative disorders.

By using the ADRM1 Polyclonal Antibody, researchers can detect and analyze the expression levels of ADRM1 in different cell types, providing valuable insights into its role in disease pathogenesis.With its specificity and reliability, the ADRM1 Polyclonal Antibody is an invaluable tool for investigations in molecular biology, proteomics, and drug discovery. By understanding the mechanisms behind ADRM1 function, researchers can potentially identify new therapeutic targets for the treatment of diseases associated with protein degradation pathways.

Product Name:ADRM1 Antibody
Product Sku:CPAB0552
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ADRM1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ADRM1 protein 1-47 amino acids purified from Ecoli.
Clone:PAT34C2AT.
Reactivity:Other bodies
Applications:ELISA, Flow Cytometry
Purification Method:ADRM1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:Proteasomal ubiquitin receptor ADRM1 (ADRM1) functions as a proteasomal ubiquitin receptor. ADRM1 is an integral plasma membrane protein which promotes cell adhesion. ADRM1 is assumed to undergo O-linked glycosylation. ADRM1 gene expression is induced by gamma interferon in some cancer cells. ADRM1 employs the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.
Synonyms:Proteasomal ubiquitin receptor ADRM1, 110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Proteasome regulatory particle non-ATPase 13, hRpn13, Rpn13 homolog, ADRM1, ARM1, Rpn13.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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