ADRA1B Rabbit Polyclonal Antibody (CAB7872)
- SKU:
- CAB7872
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ADRA1B Rabbit Polyclonal Antibody |
SKU: | CAB7872 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human ADRA1B (P35368). |
Sequence: | ADVA NGQP GFKS NMPL APGQ F |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ADRA1; ALPHA1BAR; ADRA1B |
Positive Sample: | HL-60,Jurkat,MCF7,HepG2,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein, Nucleus membrane. |
Calculated MW: | 57kDa |
Observed MW: | 50kDa |
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Purification Method: | Affinity purification |
Gene ID: | 147 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |