The ADRA1A Polyclonal Antibody (CAB1471) is a valuable tool for research involving the ADRA1A protein, a member of the alpha-1 adrenergic receptor family. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.ADRA1A is known to play a key role in regulating various physiological processes, including vasoconstriction, smooth muscle contraction, and neurotransmitter release. Dysfunction of ADRA1A has been implicated in various diseases, such as hypertension, heart failure, and benign prostatic hyperplasia.
Therefore, studying the expression and activity of ADRA1A is crucial for understanding its role in health and disease.With the ADRA1A Polyclonal Antibody, researchers can accurately detect and analyze ADRA1A protein levels in different cell types, providing valuable insights into its function in various biological processes. This antibody is an essential tool for studies in pharmacology, neurobiology, and cardiovascular research, ultimately paving the way for the development of targeted therapies for ADRA1A-related conditions.
Product Name:
ADRA1A Rabbit Polyclonal Antibody
SKU:
CAB1471
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 346-475 of human ADRA1A (NP_150646.3).
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Purification Method:
Affinity purification
Gene ID:
148
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADRA1A Rabbit pAb (CAB1471) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
