The ADPRM Polyclonal Antibody (CAB12883) is a valuable tool for researchers studying ADPRM, a key enzyme involved in DNA repair and maintenance processes. This antibody, produced in rabbits, is highly specific for detecting ADPRM in human samples and has been validated for use in Western blot applications. By binding to the ADPRM protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in the fields of DNA repair, genomics, and cancer biology.ADPRM, also known as ADP-ribose/CDP-alcohol diphosphatase, plays a crucial role in DNA damage repair mechanisms by catalyzing the hydrolysis of ADP-ribose linked to proteins.
Dysregulation of ADPRM has been implicated in various diseases, including cancer and neurodegenerative disorders. By studying the functions of ADPRM, researchers can gain insights into the molecular mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.Overall, the ADPRM Polyclonal Antibody (CAB12883) is a reliable tool for investigating the role of ADPRM in DNA repair pathways and its implications for disease development. Its specificity and sensitivity make it a valuable asset for research in molecular biology, genomics, and cancer research.
Product Name:
ADPRM Rabbit Polyclonal Antibody
SKU:
CAB12883
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 203-342 of human ADPRM (NP_064618.3).
Predicted to enable 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity; manganese ion binding activity; and pyrophosphatase activity. Predicted to be located in cytosol.
Purification Method:
Affinity purification
Gene ID:
56985
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADPRM Rabbit pAb (CAB12883) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
