The ADPRHL1 Polyclonal Antibody (CAB15553) is a valuable tool for researchers studying ADP-ribosylhydrolase like 1 (ADPRHL1), an enzyme involved in the metabolism of ADP-ribose. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ADPRHL1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and biochemistry.ADPRHL1 plays a critical role in the regulation of ADP-ribose metabolism, which is involved in various cellular processes including DNA repair, transcriptional regulation, and cell signaling. Dysregulation of ADP-ribose metabolism has been implicated in diseases such as cancer, neurodegenerative disorders, and inflammatory conditions.
Research on ADPRHL1 can provide insights into the mechanisms underlying these diseases and lead to the development of targeted therapies aimed at restoring normal ADP-ribose metabolism.By utilizing the ADPRHL1 Polyclonal Antibody, researchers can investigate the function and regulation of ADPRHL1 in different cellular contexts, providing valuable information for the development of novel therapeutic strategies. This antibody is a reliable tool for studying ADP-ribose metabolism and its implications in disease, offering researchers a powerful resource for advancing their understanding of cellular processes and disease mechanisms.
Product Name:
ADPRHL1 Rabbit Polyclonal Antibody
SKU:
CAB15553
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-280 of human ADPRHL1 (NP_612439.2).
ADP-ribosylation is a reversible posttranslational modification used to regulate protein function. ADP-ribosyltransferases (see ART1; MIM 601625) transfer ADP-ribose from NAD+ to the target protein, and ADP-ribosylhydrolases, such as ADPRHL1, reverse the reaction (Glowacki et al., 2002 [PubMed 12070318]).
Purification Method:
Affinity purification
Gene ID:
113622
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADPRHL1 Rabbit pAb (CAB15553) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3s.
