The ADORA3 Polyclonal Antibody (CAB18524) is a valuable tool for research involving the ADORA3 protein, a G-protein coupled receptor that plays a key role in mediating the effects of adenosine, a signaling molecule involved in various physiological processes. This antibody, raised in rabbits, is highly specific and reacts with human samples, making it suitable for use in Western blot applications.ADORA3 is known to be involved in immune regulation, inflammation, and cardiovascular function, making it a promising target for research in immunology, cardiovascular biology, and drug development. By binding to the ADORA3 protein, this antibody enables the detection and analysis of ADORA3 expression in different cell types, providing valuable insights into its role in various biological processes.
The ADORA3 Polyclonal Antibody is a valuable tool for researchers interested in studying the functions of adenosine receptors and their implications in health and disease. Its high specificity and reactivity with human samples make it an ideal choice for studies aiming to elucidate the molecular mechanisms underlying the actions of ADORA3, paving the way for the development of novel therapeutic strategies targeting this important receptor.
Product Name:
ADORA3 Polyclonal Antibody
SKU:
CAB18524
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ADORA3 (NP_000668.1).
This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein.
Purification Method:
Affinity purification
Gene ID:
140
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ADORA3 Rabbit pAb (CAB18524) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
