The Adora2b Polyclonal Antibody (CAB1953) is a crucial tool for researchers studying Adora2b, a cell surface receptor involved in various physiological processes, including inflammation, immune response, and cardiovascular function. This antibody, produced in rabbits, has been rigorously validated for use in Western blot applications and exhibits high reactivity with human samples.Adora2b, also known as the adenosine A2B receptor, is a G protein-coupled receptor that plays a key role in regulating adenosine-mediated signaling pathways. Its involvement in modulating immune responses, inflammation, and tissue repair makes it a promising target for therapeutic interventions in conditions such as cardiovascular disease, cancer, and inflammatory disorders.
By specifically binding to the Adora2b protein, this polyclonal antibody enables precise detection and analysis of Adora2b expression in various cell types. Its reliability and specificity make it an essential tool for researchers investigating the physiological and pathological roles of Adora2b, ultimately contributing to the development of novel therapeutic strategies targeting the adenosine signaling pathway.
Product Name:
ADORA2B Rabbit Polyclonal Antibody
SKU:
CAB1953
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ADORA2B (NP_000667.1).
This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.
Purification Method:
Affinity purification
Gene ID:
136
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ADORA2B antibody (CAB1953) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
