The Adora1 Polyclonal Antibody (CAB18525) is a valuable tool for researchers studying adenosine receptor A1 (Adora1), a protein known for its role in various physiological processes, including neurotransmission and inflammation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Adora1 is a G protein-coupled receptor that binds to the neurotransmitter adenosine and plays a crucial role in regulating neuronal activity and synaptic transmission.
Its involvement in modulating inflammation also makes it a potential therapeutic target for conditions such as neurodegenerative diseases and chronic pain.By binding specifically to the Adora1 protein, this polyclonal antibody enables researchers to detect and analyze its expression in different cell types, providing valuable insights into its function and potential implications for disease pathology. Its versatility and reliability make it an essential tool for studies in neuroscience, immunology, and pharmacology.
Product Name:
ADORA1 Rabbit Polyclonal Antibody
SKU:
CAB18525
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-326 of human ADORA1 (NP_000665.1).
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
134
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse heart, using ADORA1 Rabbit pAb (CAB18525) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1min.
