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ADO Antibody (PACO07622)

SKU:
PACO07622
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$551

Description

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ADO Antibody (PACO07622)

The ADO Antibody (PACO07622) is a highly specific polyclonal antibody designed for researchers studying the ADO protein, which plays a key role in immune regulation. Raised in rabbits, this antibody is especially reactive with human samples and is validated for use in various applications, including Western blotting.ADO, also known as adenosine deaminase, is an enzyme involved in purine metabolism and plays a crucial role in regulating immune responses. By binding to the ADO protein, this antibody enables researchers to detect and analyze ADO levels in different cell types, making it an invaluable tool for studies in immunology and cancer research.

The importance of ADO in immune response modulation highlights its potential as a target for therapeutic interventions in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By understanding the activity of ADO, researchers can develop novel therapies that manipulate immune function for improved treatment outcomes.

Antibody Name:ADO Antibody (PACO07622)
Antibody SKU:PACO07622
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human ADO
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:2-aminoethanethiol (cysteamine) dioxygenase;ADO;C10orf22;DKFZp564C046;FLJ14547 ;
UniProt Protein Function:ADO:
UniProt Protein Details:

Protein type:EC 1.13.11.19; Oxidoreductase; Other Amino Acids Metabolism - taurine and hypotaurine

Chromosomal Location of Human Ortholog: 10q21.3

Cellular Component: mitochondrion

Molecular Function:metal ion binding; cysteamine dioxygenase activity

NCBI Summary:Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]).[supplied by OMIM, Mar 2008]
UniProt Code:Q96SZ5
NCBI GenInfo Identifier:88984104
NCBI Gene ID:84890
NCBI Accession:Q96SZ5.2
UniProt Related Accession:Q96SZ5
Molecular Weight:30kDa
NCBI Full Name:2-aminoethanethiol dioxygenase
NCBI Synonym Full Names:2-aminoethanethiol dioxygenase
NCBI Official Symbol:ADO  
NCBI Official Synonym Symbols:C10orf22  
NCBI Protein Information:2-aminoethanethiol dioxygenase
UniProt Protein Name:2-aminoethanethiol dioxygenase
UniProt Synonym Protein Names:Cysteamine dioxygenase
Protein Family:AdoMet-dependent rRNA methyltransferase
UniProt Gene Name:ADO  
UniProt Entry Name:AEDO_HUMAN

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